Members in italics are clinical researchers
Dr. Phillip Baldwin
Columbia Oncology Associates
Seven Richland Medical Park Drive, Ste 201
Columbia, SC 29203
Dr. Frank Berger
USC - Dept of Biological Sciences
CLS 401
Columbia, SC 29208
Dr. Frank Berger – His laboratory interests are the mechanisms of colon cancer carcinogenesis. He is the principal investigator of the COBRE grant.
Dr. Sondra Berger
USC - College of Pharmacy
Columbia, SC 29208
Dr. Sondra Berger – Her laboratory interests center around, thymidylate synthetase, an enzyme involved in the metabolism of flurouracil.
Dr. Katryna Bogovich
USC School of Medicine
Bldg 28, 1st Floor
Columbia, SC 29208
Dr. Franklyn Bolander
USC - Dept of Biological Sciences
Columbia, SC 29208
Dr. Roberd Bostick
South Carolina Cancer Center
Division of Population Studies
Fifteen Richland Medical Park Drive, Suite 301
Columbia, SC 29203
Dr. Robin Bostick – His laboratory interests include identifying and developing biomarkers for cancer. He is the principal investigator in a large colon cancer prevention project in patients who are known to have colonic polyps.
Dr. James Boulware
Palmetto Richland - Radiation Oncology
Seven Richland Medical Park Drive
Columbia, SC 29208
Dr. William E. Bowers
USC - Dept of Mirco and Immuno
SMC 662 C-5
Columbia, SC 29208
Dr. Marlyn Boyd
USC College of Nursing
USC - Nur 201
Columbia, SC 29208
Dr. William M. Butler
South Carolina Oncology Associates
Seven Richland Medical Park Drive, Suite 201
Columbia, SC 29203
Dr. Neal Christiansen
South Carolina Oncology Associates
Two Richland Medical Park Drive, Suite 201
Columbia, SC 29203
Dr. Ann Coker
USC - Dept of Epi and Biostat
HESC 205C
Columbia, SC 29208
Dr. Kim Creek
USC - Dept of Pathology
USC - SOM Bldg 4
Columbia, SC 2920
Drs. Kim E. Creek and Lucia Pirisi – Their work investigates the role of the EGF receptor (EGFR) in HPV16-mediated transformation of human epithelial cells and in the neoplastic progression of HPV16 transformed cells. They just received major funding from the NIH and plan to use this funding to add 3 additional graduate students to their research team. This will be in addition to the 4 graduate students currently under their mentorship. They are working to complete establishment of the microarray facility at the SCCC and to make it fully operational by the end of the year.
Dr. Joan Cunningham
South Carolina Cancer Center
Division of Population Studies
Fifteen Richland Medical Park Drive, Suite 301
Columbia, SC 29203
Dr. Joan Cunningham – Her research interests are primarily in the area of breast cancer. She is involved in a study of ultrasound as a predictor of lymph node metastasis and she is involved in the study of ethnic differences in breast cancer grade. She is also active in several areas of cancer epidemiology.
Dr. Tommy Cupples
South Carolina Comprehensive Breast Center
Palmetto Richland Memorial Hospital
1 Richland Medical Park Drive, Ste 120
Columbia, SC 29203
Dr. Michael V. Dewey
USC - Dept of Biology
Columbia, SC 29208
Dr. Bruce Dunlap
USC - Chemistry and Biochemistry
Columbia, SC 29208
Dr. Francisco Gonzalez
Palmetto Richland - Dept of Internal Medicine
Seven Richland Medical Park Drive, Suite 202
Columbia, SC 29203
Dr. James Hebert
USC – School of Public Health
Chair, Epidemiology & Biostatistics
Columbia, SC 29208
Dr. James Hebert has spent most of his career with studies aimed at investigating the role of diet in cancer and cardiovascular disease. This work has been based in a number of different settings (including the U.S. and India) A major theme of the past 15 years has been on improving methods of dietary assessment so as to obviate errors in self-reporting that can cause serious problems with interpreting data from epidemiologic studies. Research priorities in the next five years include: Continued improvements in methods of measuring diet, expansion of the research base to include populations that are normally not part of conventional research studies, developing methods of intervening on diet and physical activity, and employing epidemiologic methods to investigate non-conventional approaches to cancer survival.
Dr. Sue Heiney
South Carolina Cancer Center - Psychosocial Services
Seven Richland Medical Park Drive
Columbia, SC 29203
Dr. Sue P. Heiney completed descriptive a data analysis looking at the efficacy of therapeutic groups for women with breast cancer and is working on a statistical analysis for this project. She is also involved in a psychosocial and walking intervention for breast cancer.
Dr. Paul Housley
USC - Dept of Pharmacology
SMC 661 D-8
Columbia, SC 29208
Dr. Paul R. Housley is studying how the oncogenes Hras and c-jun repress GR gene transcription. An incoming summer research intern will insert the two candidate fragments of the GR promoter into heterologous promoters to determine if these sequences can function as c-Jun-dependent repressors, independent of the GR promoter context.
Dr. William Hrushesky
Dorn VAMC (151)
Director, Research & Development
Columbia, SC 29209
Dr. William Hrushesky and Dr. Patricia Wood – The VA program has shown tremendous growth under the leadership of Dr. Hrushesky and Dr. Woods. The SCCC-VA division has rapidly expanded and been successful in achieving funding, carrying out and publishing basic, translational and clinical research findings. Some of the projects include studying the chronobiology estrogen in breast cancer and work in prostate cancer. They are actively working with other researchers in the SCCC.
Dr. Lawrence Lamb
South Carolina Cancer Center
Palmetto Richland - Bone Marrow Transplantation
Seven Richland Medical Park Drive
Columbia, SC 29203
Dr. Lawrence Lamb – His research is focused on determining the phenotype, clonality, activation state, and cytotoxicity to the leukemia of __ + T cells from patients with acute leukemia. H is working to learn if a __ + T cell specific autologous or allogeneic graft-versus-leukemia effect can be replicated in vitro by expanding cytotoxic __ + T cells against acute leukemia. He plans to identify and clone the receptor on ALL that binds to __ + T cells or a relevant inhibitor using molecular and proteomics techniques.
Dr. Katherine Lind
USC – Institute of Public Affairs
Survey Research Laboratory
Columbia, SC 29208
Dr. Steven Madden
PO Box 2046
W. Cola, SC 29171
Dr. Chuck Matthews
USC – School of Public Health
Columbia, SC 29203
Dr. C. E Matthews is studying physical activity, energy balance, and colon cancer risk. He hopes to develop and refine hypotheses concerning the biologic mechanisms through which physical activity reduces risk for colon cancer. He is also studying cardiorespiratory fitness and functional status among women with breast cancer.
Dr. James A. McFarland
South Carolina Cancer Center
Palmetto Richland - Oncology
Seven Richland Medical Park Drive
Columbia, SC 29203
Dr. Kevin McRedmond
Palmetto Richland - Bone Marrow Transplantation
Seven Richland Medical Park Drive, Ste 203
Columbia, SC 29203
Dr. Carolyn Murdaugh
USC – College of Nursing
Columbia, SC 29203
Dr. Stephanie Muga
South Carolina Cancer Center
Basic Science Division
Fourteen Richland Medical Park, Suite 500
Columbia, SC 29203
Dr. Stephanie J. Muga – The major focus of her laboratory is to understand the molecular mechanisms that modulate normal and abnormal growth. Under normal conditions, growth and differentiation processes are highly orchestrated events. Understanding the mechanism by which these processes goes awry will provide valuable insights into the pathophysiology of human illness and disease. Her primary research interests are focused on elucidating the functional role that lipids (fatty acids) play in regulation or dysregulation during onset of rapid growth. Her research focuses on understanding the functions and mechanisms of action of arachidonic acid metabolites in various models of carcinogenesis.
Dr. William Neglia
South Carolina Cancer Center
Seven Richland Medical Park Drive, Ste 104
Columbia, SC 29203
Dr. Ron Neuberg
South Carolina Cancer Center
Palmetto Richland - Peds Hem/Onc
Seven Richland Medical Park Drive, Ste 203
Columbia, SC 29203
Dr. Harris Pastides
USC - School of Public Health
HESC 101
Columbia, SC 29208
Dr. Rekha Patel
USC - Dept of Biology
Columbia, SC 29208
Dr. Jeffrey Patton
Dept of Pathology
USC School of Medicine
Columbia, SC 29208
Dr. Jeffrey R. Patton – His laboratory is interested in discovering new protein factors that are involved in the alternative splicing of pre-messenger RNA and they have begun to use C. elegans as a model system to define the roles of these factors prior to investigating the role of their homologues in humans.
Dr. Lucia Pirisi-Creek
USC - Dept of Pathology
SOM Bldg 1 C-2
Columbia, SC 29208
Drs. Lucia Pirisi and Kim E. Creek – Their work investigates the role of the EGF receptor (EGFR) in HPV16-mediated transformation of human epithelial cells and in the neoplastic progression of HPV16 transformed cells. They just received major funding from the NIH and plan to use this funding to add 3 additional graduate students to their research team. This will be in addition to the 4 graduate students currently under their mentorship. They are working to complete establishment of the microarray facility at the SCCC and to make it fully operational by the end of the year.
Dr. Robert Price
University of South Carolina
Director, Imaging Center
Columbia, SC 29208
Dr. David Reisman
USC - Dept of Biological Sciences
Columbia, SC 29208
Dr. David Reisman is trying to determine the role that missense mutations in the p53 tumor suppressor play in transcriptional regulation and in oncogenesis and how these oncogenic p53 alleles are overexpressed in tumor cells. They are currently studying the effect of p53 missense mutations on colon tumor incidence in mice and to determine the contribution of mutant p53 to colon tumorigenesis in cooperation with the loss of wt p53 and the Min allele.
Dr. Maureen Sanderson
USC - Dept of Epidemiology and Biostatistics
Columbia, SC 29208
Dr. Xiao - Ou Shu
South Carolina Cancer Center
Div of Population Studies
Fifteen Richland Medical Park Drive, Ste 301
Columbia, SC 29203
Dr. Terry Smith
South Carolina Cancer Center
Palmetto Richland - Oncology
Seven Richland Medical Park Drive
Columbia,SC 29208
Dr. Trent Spencer
USC - Dept of Chemistry
Fourteen Richland Medical Park Drive
Columbia, SC 29208
Dr. Jane Teas
South Carolina Cancer Center
Population Studies Division
Fifteen Medical Park, Suite 301
Columbia, SC 29203
Dr. Jane Teas is most interested in the health effects of alternative therapies, including dietary seaweed, faith and healing, macrobiotics and cancer. In 2001, Dr. Teas focused on two complementary therapies with curative intent, faith practices among Charismatic Christians and macrobiotics and cancer, both parts of her grant from the Centers for Disease Control.
Dr. Diane W. Truesdale
South Carolina Cancer Center
Palmetto Richland - Radiology Oncology
Seven Richland Medical Park Drive
Columbia, SC 29203
Dr. Michael Wargovich
South Carolina Cancer Center
Division of Translational Research
Fourteen Richland Medical Park Drive
Columbia, SC 29203
Dr. Michael Wargovich – This laboratory is focused on cancer prevention. They will be involved in a project with Dr. Stephanie Muga to investigate the effects of diet of colon cancer chemotherapy in a mouse model for colon cancer. The laboratory is in a strong position to capitalize on its expertise in cancer chemoprevention to begin to translate these programs into clinical research. Long-term goals are to secure an Academic Leadership Award from NIH in Cancer Complementary and Alternative Medicine.
Dr. James R. Wells
Nine Richland Medical Park Drive, Suite 510
Columbia, SC 29203
Dr. James A. Williams, Jr
South Carolina Cancer Center
Palmetto Richland - Dept of OB/Gyn Oncology
Two Richland Medical Park Drive, Ste 208
Columbia, SC 29203
Dr. Rudolph Wise
South Carolina Cancer Center
Seven Richland Medical Park Drive, Ste 201
Columbia, SC 29203
Dr. Patricia Wood
Dorn VAMC
Research & Development
Columbia, SC 29209
Dr. Patricia Wood and Dr. William Hrushesky – The VA program has shown tremendous growth under the leadership of Dr. Hrushesky and Dr. Woods. The SCCC-VA division has rapidly expanded and been successful in achieving funding, carrying out and publishing basic, translational and clinical research findings. Some of the projects include studying the chronobiology estrogen in breast cancer and work in prostate cancer. They are actively working with other researchers in the SCCC.
Dr. Da-wen Xie
South Carolina Cancer Center - Div of Population Studies
Fourteen Richland Medical Park Drive, Ste 301
Columbia, SC 29203
Dr. D. Xie has his primary research interest is the field of molecular epidemiology. He is working with a panel of genetic susceptibility markers to identify high-risk subgroups and to explore interactions between host genetic factors and environment factors. He is working with colorectal cancer and prostate cancer. He recently received his first NIH grant.
Dr. Robert Young
USC - Dept of OB/Gyn
Two Richland Medical Park Drive, Ste 208
Columbia, SC 29203
Dr. Robert Young continues his studies of the molecular cytogenetic characteristics of breast and gynecologic malignancies and further developed the cancer genetic counseling effort. He adapted the fluorescence in situ hybridization (FISH) technique for the oncogene HER-2 from paraffin embedded sample study to a direct "touch" methodology. His genetic counseling program is the most active program in South Carolina.
